The Migeotte Laboratory
Welcome to the Laboratory website
Our research studies the cellular, molecular, and mechanical mechanisms of coordinated migration, in which cells are physically and/or functionally connected, using the early mouse embryo as a model. Collective migration is essential for morphogenetic movements during embryogenesis, as well as for major physiological (such as wound healing) and pathological (such as cancer invasion) processes during adult life. The laboratory has two major research axes:
Anterior Visceral Endoderm migration as a model of epithelial collective migration.
Mesoderm migration as a model of epithelial-mesenchymal transition followed by cell sheet migration.